| Week 5 | ||||
| SUN, OCT 5 | TIME | TV | RESOURCES | LOCATION |
| Kansas City at Carolina | 1:00 PM | CBS | Tickets | | Bank of America Stadium |
| Chicago at Detroit | 1:00 PM | Fox | Tickets | | Ford Field |
| Atlanta at Green Bay | 1:00 PM | Fox | Tickets | | Lambeau Field |
| San Diego at Miami | 1:00 PM | CBS | Tickets | | Dolphin Stadium |
| Seattle at NY Giants | 1:00 PM | Fox | Tickets | | Giants Stadium |
| Washington at Philadelphia | 1:00 PM | Fox | Tickets | | Lincoln Financial Field |
| Tennessee at Baltimore | 1:00 PM | CBS | Tickets | | M&T Bank Stadium |
| Indianapolis at Houston | 1:00 PM | CBS | Tickets | | Reliant Stadium |
| Tampa Bay at Denver | 4:05 PM | Fox | Tickets | | Invesco Field |
| Buffalo at Arizona | 4:15 PM | CBS | Tickets | | U of Phoenix Stadium |
| New England at San Francisco | 4:15 PM | CBS | Tickets | | Monster Park |
| Cincinnati at Dallas | 4:15 PM | CBS | Tickets | | Texas Stadium |
| Pittsburgh at Jacksonville | 8:15 PM | NBC | Tickets | | Jacksonville Stadium |
| MON, OCT 6 | TIME | TV | RESOURCES | LOCATION |
| Minnesota at New Orleans | 8:30 PM | ESPN | Tickets | | Superdome |
| ·Bye: Cleveland, Oakland, St. Louis, NY Jets | ||||
| Week 6 | ||||
| SUN, OCT 12 | TIME | TV | RESOURCES | LOCATION |
| Chicago at Atlanta | 1:00 PM | Fox | Tickets | | Georgia Dome |
| Baltimore at Indianapolis | 1:00 PM | CBS | Tickets | | Lucas Oil Stadium |
| Detroit at Minnesota | 1:00 PM | Fox | Tickets | | Metrodome |
| Oakland at New Orleans | 1:00 PM | CBS | Tickets | | Superdome |
| Cincinnati at NY Jets | 1:00 PM | CBS | Tickets | | Giants Stadium |
| Carolina at Tampa Bay | 1:00 PM | Fox | Tickets | | Raymond James Stadium |
| St. Louis at Washington | 1:00 PM | Fox | Tickets | | FedEx Field |
| Miami at Houston | 1:00 PM | CBS | Tickets | | Reliant Stadium |
| Jacksonville at Denver | 4:05 PM | CBS | Tickets | | Invesco Field |
| Dallas at Arizona | 4:15 PM | Fox | Tickets | | U of Phoenix Stadium |
| Philadelphia at San Francisco | 4:15 PM | Fox | Tickets | | Monster Park |
| Green Bay at Seattle | 4:15 PM | Fox | Tickets | | Qwest Field |
| New England at San Diego | 8:15 PM | NBC | Tickets | | Qualcomm Stadium |
| MON, OCT 13 | TIME | TV | RESOURCES | LOCATION |
| NY Giants at Cleveland | 8:30 PM | ESPN | Tickets | | Cleveland Browns Stadium |
| ·Bye: Buffalo, Tennessee, Kansas City, Pittsburgh | ||||
| Week 7 | ||||
| SUN, OCT 19 | TIME | TV | RESOURCES | LOCATION |
| San Diego at Buffalo | 1:00 PM | CBS | Tickets | | Ralph Wilson Stadium |
| Minnesota at Chicago | 1:00 PM | Fox | Tickets | | Soldier Field |
| Pittsburgh at Cincinnati | 1:00 PM | CBS | Tickets | | Paul Brown Stadium |
| Tennessee at Kansas City | 1:00 PM | CBS | Tickets | | Arrowhead Stadium |
| Dallas at St. Louis | 1:00 PM | Fox | Tickets | | Edward Jones Dome |
| Baltimore at Miami | 1:00 PM | CBS | Tickets | | Dolphin Stadium |
| San Francisco at NY Giants | 1:00 PM | Fox | Tickets | | Giants Stadium |
| New Orleans at Carolina | 1:00 PM | Fox | Tickets | | Bank of America Stadium |
| Detroit at Houston | 4:05 PM | Fox | Tickets | | Reliant Stadium |
| NY Jets at Oakland | 4:15 PM | CBS | Tickets | | McAfee Coliseum |
| Indianapolis at Green Bay | 4:15 PM | CBS | Tickets | | Lambeau Field |
| Cleveland at Washington | 4:15 PM | CBS | Tickets | | FedEx Field |
| Seattle at Tampa Bay | 8:15 PM | NBC | Tickets | | Raymond James Stadium |
| MON, OCT 20 | TIME | TV | RESOURCES | LOCATION |
| Denver at New England | 8:30 PM | ESPN | Tickets | | Gillette Stadium |
| ·Bye: Atlanta, Philadelphia, Arizona, Jacksonville | ||||
| Week 8 | ||||
| SUN, OCT 26 | TIME | TV | RESOURCES | LOCATION |
| Tampa Bay at Dallas | 1:00 PM | Fox | Tickets | | Texas Stadium |
| Washington at Detroit | 1:00 PM | Fox | Tickets | | Ford Field |
| Buffalo at Miami | 1:00 PM | CBS | Tickets | | Dolphin Stadium |
| St. Louis at New England | 1:00 PM | Fox | Tickets | | Gillette Stadium |
| San Diego at New Orleans | 1:00 PM | CBS | Tickets | | Wembley Stadium |
| Kansas City at NY Jets | 1:00 PM | CBS | Tickets | | Giants Stadium |
| Atlanta at Philadelphia | 1:00 PM | Fox | Tickets | | Lincoln Financial Field |
| Oakland at Baltimore | 1:00 PM | CBS | Tickets | | M&T Bank Stadium |
| Arizona at Carolina | 1:00 PM | Fox | Tickets | | Bank of America Stadium |
| Cleveland at Jacksonville | 4:05 PM | CBS | Tickets | | Jacksonville Stadium |
| Cincinnati at Houston | 4:05 PM | CBS | Tickets | | Reliant Stadium |
| NY Giants at Pittsburgh | 4:15 PM | Fox | Tickets | | Heinz Field |
| Seattle at San Francisco | 4:15 PM | Fox | Tickets | | Monster Park |
| MON, OCT 27 | TIME | TV | RESOURCES | LOCATION |
| Indianapolis at Tennessee | 8:30 PM | ESPN | Tickets | | LP Field |
| ·Bye: Chicago, Denver, Green Bay, Minnesota | ||||
| Week 9 | ||||
| SUN, NOV 2 | TIME | TV | RESOURCES | LOCATION |
| NY Jets at Buffalo | 1:00 PM | CBS | Tickets | | Ralph Wilson Stadium |
| Detroit at Chicago | 1:00 PM | Fox | Tickets | | Soldier Field |
| Jacksonville at Cincinnati | 1:00 PM | CBS | Tickets | | Paul Brown Stadium |
| Baltimore at Cleveland | 1:00 PM | CBS | Tickets | | Cleveland Browns Stadium |
| Green Bay at Tennessee | 1:00 PM | Fox | Tickets | | LP Field |
| Tampa Bay at Kansas City | 1:00 PM | Fox | Tickets | | Arrowhead Stadium |
| Arizona at St. Louis | 1:00 PM | Fox | Tickets | | Edward Jones Dome |
| Houston at Minnesota | 1:00 PM | CBS | Tickets | | Metrodome |
| Miami at Denver | 4:05 PM | CBS | Tickets | | Invesco Field |
| Dallas at NY Giants | 4:15 PM | Fox | Tickets | | Giants Stadium |
| Philadelphia at Seattle | 4:15 PM | Fox | Tickets | | Qwest Field |
| Atlanta at Oakland | 4:15 PM | Fox | Tickets | | McAfee Coliseum |
| New England at Indianapolis | 8:15 PM | NBC | Tickets | | Lucas Oil Stadium |
| MON, NOV 3 | TIME | TV | RESOURCES | LOCATION |
| Pittsburgh at Washington | 8:30 PM | ESPN | Tickets | | FedEx Field |
| ·Bye: New Orleans, San Diego, San Francisco, Carolina | ||||
| Week 10 | ||||
| THU, NOV 6 | TIME | TV | RESOURCES | LOCATION |
| Denver at Cleveland | 8:15 PM | NFL | Tickets | | Cleveland Browns Stadium |
| SUN, NOV 9 | TIME | TV | RESOURCES | LOCATION |
| New Orleans at Atlanta | 1:00 PM | Fox | Tickets | | Georgia Dome |
| Tennessee at Chicago | 1:00 PM | CBS | Tickets | | Soldier Field |
| Jacksonville at Detroit | 1:00 PM | CBS | Tickets | | Ford Field |
| Seattle at Miami | 1:00 PM | Fox | Tickets | | Dolphin Stadium |
| Green Bay at Minnesota | 1:00 PM | Fox | Tickets | | Metrodome |
| Buffalo at New England | 1:00 PM | CBS | Tickets | | Gillette Stadium |
| St. Louis at NY Jets | 1:00 PM | Fox | Tickets | | Giants Stadium |
| Baltimore at Houston | 1:00 PM | CBS | Tickets | | Reliant Stadium |
| Carolina at Oakland | 4:05 PM | Fox | Tickets | | McAfee Coliseum |
| Indianapolis at Pittsburgh | 4:15 PM | CBS | Tickets | | Heinz Field |
| Kansas City at San Diego | 4:15 PM | CBS | Tickets | | Qualcomm Stadium |
| NY Giants at Philadelphia | 8:15 PM | NBC | Tickets | | Lincoln Financial Field |
| MON, NOV 10 | TIME | TV | RESOURCES | LOCATION |
| San Francisco at Arizona | 8:30 PM | ESPN | Tickets | | U of Phoenix Stadium |
| ·Bye: Dallas, Tampa Bay, Washington, Cincinnati | ||||
| Week 11 | ||||
| THU, NOV 13 | TIME | TV | RESOURCES | LOCATION |
| NY Jets at New England | 8:15 PM | NFL | Tickets | | Gillette Stadium |
| SUN, NOV 16 | TIME | TV | RESOURCES | LOCATION |
| Denver at Atlanta | 1:00 PM | CBS | Tickets | | Georgia Dome |
| Philadelphia at Cincinnati | 1:00 PM | Fox | Tickets | | Paul Brown Stadium |
| Chicago at Green Bay | 1:00 PM | Fox | Tickets | | Lambeau Field |
| Houston at Indianapolis | 1:00 PM | CBS | Tickets | | Lucas Oil Stadium |
| New Orleans at Kansas City | 1:00 PM | Fox | Tickets | | Arrowhead Stadium |
| Oakland at Miami | 1:00 PM | CBS | Tickets | | Dolphin Stadium |
| Baltimore at NY Giants | 1:00 PM | CBS | Tickets | | Giants Stadium |
| Minnesota at Tampa Bay | 1:00 PM | Fox | Tickets | | Raymond James Stadium |
| Detroit at Carolina | 1:00 PM | Fox | Tickets | | Bank of America Stadium |
| Tennessee at Jacksonville | 1:00 PM | CBS | Tickets | | Jacksonville Stadium |
| St. Louis at San Francisco | 4:05 PM | Fox | Tickets | | Monster Park |
| Arizona at Seattle | 4:05 PM | Fox | Tickets | | Qwest Field |
| San Diego at Pittsburgh | 4:15 PM | CBS | Tickets | | Heinz Field |
| Dallas at Washington | 8:15 PM | NBC | Tickets | | FedEx Field |
| MON, NOV 17 | TIME | TV | RESOURCES | LOCATION |
| Cleveland at Buffalo | 8:30 PM | ESPN | Tickets | | Ralph Wilson Stadium |
| Week 12 | ||||
| THU, NOV 20 | TIME | TV | RESOURCES | LOCATION |
| Cincinnati at Pittsburgh | 8:15 PM | NFL | Tickets | | Heinz Field |
| SUN, NOV 23 | TIME | TV | RESOURCES | LOCATION |
| Carolina at Atlanta | 1:00 PM | Fox | Tickets | | Georgia Dome |
| Houston at Cleveland | 1:00 PM | CBS | Tickets | | Cleveland Browns Stadium |
| San Francisco at Dallas | 1:00 PM | Fox | Tickets | | Texas Stadium |
| Tampa Bay at Detroit | 1:00 PM | Fox | Tickets | | Ford Field |
| NY Jets at Tennessee | 1:00 PM | CBS | Tickets | | LP Field |
| Buffalo at Kansas City | 1:00 PM | CBS | Tickets | | Arrowhead Stadium |
| Chicago at St. Louis | 1:00 PM | Fox | Tickets | | Edward Jones Dome |
| New England at Miami | 1:00 PM | CBS | Tickets | | Dolphin Stadium |
| Minnesota< | ||||