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| Date | Opponent | Time | Location |
| Friday, Feb 29 | @ Cincinnati Reds | 1:05 p.m. | Sarasota |
| Saturday, Mar 1 | Toronto Blue Jays | 1:05 p.m. | St. Petersburg |
| Sunday, Mar 2 | @ Pittsburgh Pirates | 1:05 p.m. | Bradenton |
| Monday, Mar 3 | @ Detroit Tigers | 1:05 p.m. | Lakeland |
| Tuesday, Mar 4 | Minnesota Twins | 1:05 p.m. | St. Petersburg |
| Wednesday, Mar 5 | Houston Astros | 1:05 p.m. | St. Petersburg |
| Thursday, Mar 6 | @ Philadelphia Phillies | 1:05 p.m. | Clearwater |
| Friday, Mar 7 | Philadelphia Phillies | 1:05 p.m. | St. Petersburg |
| Saturday, Mar 8 | @ New York Yankees | 1:05 p.m. | Tampa |
| Sunday, Mar 9 | Cincinnati Reds | 1:05 p.m. | St. Petersburg |
| Monday, Mar 10 | Cleveland Indians | 1:05 p.m. | St. Petersburg |
| Tuesday, Mar 11 | @ Minnesota Twins | 1:05 p.m. | Fort Myers |
| Wednesday, Mar 12 | New York Yankees | 1:05 p.m. | St. Petersburg |
| Thursday, Mar 13 | @ Boston Red Sox | 1:05 p.m. | Fort Myers |
| Friday, Mar 14 | Toronto Blue Jays | 1:05 p.m. | St. Petersburg |
| Saturday, Mar 15 | @ Atlanta Braves (SS) | 1:05 p.m. | Celebration City |
| @New York Yankees (SS) | 1:05 p.m. | Tampa | |
| Sunday, Mar 16 | Detroit Tigers | 1:05 p.m. | St. Petersburg |
| Tuesday, Mar 18 | @ Philadelphia Phillies | 1:05 p.m. | Clearwater |
| Wednesday, Mar 19 | Philadelphia Phillies | 1:05 p.m. | St. Petersburg |
| Thursday, Mar 20 | Cleveland Indians | 1:05 p.m. | St. Petersburg |
| Friday, Mar 21 | @ New York Yankees | 1:05 p.m. | Tampa |
| Saturday, Mar 22 | Pittsburgh Pirates | 1:05 p.m. | St. Petersburg |
| Sunday, Mar 23 | @ Cincinnati Reds | 1:05 p.m. | Sarasota |
| Monday, Mar 24 | Pittsburgh Pirates | 1:05 p.m. | St. Petersburg |
| Tuesday, Mar 25 | @ Toronto Blue Jays | 1:05 p.m. | Dunedin |
| Wednesday, Mar 26 | @ Minnesota Twins | 1:05 p.m. | Fort Myers |
| Thursday, Mar 27 | @ Cleveland Indians | 1:05 p.m. | Winter Haven |
| Friday, Mar 28 | Cincinnati Reds | 1:05 p.m. | St. Petersburg |
| Saturday, Mar 29 | @ Cincinnati Reds | 1:05 p.m. | Sarasota |
| SS = Split Squad | |||
| Bold = Home Games | |||